Fig. 2. Pharmacological therapy strategies for hepatic antifibrosis.
Abbreviations: ACE, angiotensin converting enzyme inhibitors; CB1, cannabinoid receptor 1; CCR, CC chemokine receptor; DAA, direct-acting antiviral agents; ECM, extracellular matrix; FGF, fibroblast growth factor; FXR, farnesoid X receptor; HSC, hepatic stellate cell; NA, nucleos(t)ide analog; NK, natural killer; PPARs, peroxisome proliferator-activated receptor; TGF, transforming growth factor; LOXL2, lysyl oxidase-like protein 2; TIMP, tissue inhibitor of metalloproteinase.