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. 2020 Aug 19;68(4):24. doi: 10.1007/s00005-020-00590-6

Table 2.

Distribution of RANK (rs8086340, C > G; rs1805034, C > T) and RANKL (rs7325635, G > A; rs7988338 G > A) genotypes in RA patients and controls

Gene Genotype RA patients N (%) Controls N (%)

RANK

rs8086340

CC 37 (11.7%)a 31 (19.0%)
CG 155 (48.9%)b 63 (38.7%)
GG 125 (39.4%) 69 (42.3%)

RANK

rs1805034

CC 65 (20.4%) 37 (22.7%)
CT 153 (48.1%) 80 (49.1%)
TT 100 (31.5%) 46 (28.2%)

RANKL

rs7325635

GG 98 (30.8%) 44 (27.2%)
GA 147 (46.2%) 87 (53.7%)
AA 73 (23.0%) 31 (19.1%)

RANKL

rs7988338

GG 219 (68.9%) 107 (65.6%)
GA 91 (28.6%) 50 (30.7%)
AA 8 (2.52%) 6 (3.63%)

N number of individuals with a given genotype

aOR = 1.777, 95% CI (1.069–3.010), p = 0.038

bOR = 1.519, 95% CI (1.039–2.227), p = 0.034