Table 2.
Author | Year | Number SRC-GC | Description SRC-GC | Classification tumour type used | Mucin stains (% positivea) | Relationship with survival | Comparison with other tumour types | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
n | % | MUC2 | MUC5AC | MUC6 | EMA/MUC1 | Yes/No | |||||
Sakamoto H | 1997 | 38 | 17 | No | No | 66 | NA | NA | 7 | Yes | Yes |
Baldus SE | 1998 | 62 | 48 | No | WHOb, Lauren | 27 | NA | NA | 60/45 | Yes | Yes |
Gürbüz Y | 2002 | 31 | 19 | Yes | No | 81 | 100 | 35 | 52 | NR | Yes |
Akyürek N | 2002 | 37 | 26 | No | Borrmann, WHOc, Lauren | 41 | NA | NA | 43 | NS | Yes |
Aihara R | 2004 | 69 | 100 | Yes | WHOb, JGCA | 41 | 100 | 38 | NA | Yes | No |
Chu PG | 2004 | 30 | 100 | Yes | No | 50 | 50 | NA | 17 | NR | No |
Zhang HK | 2004 | 31 | 33 | No | no | 81 | 55 | 71 | NA | NS | Yes |
Nguyen MD | 2006 | 21 | 100 | Yes | No | 48 | 38 | 29 | 24 | NR | No |
Sentani K | 2008 | 21 | 100 | Yes | No | 71 | 48 | NA | NA | NR | No |
Chiaravalli AM | 2009 | 24 | 20 | Yes | Own | 60 | 60 | NA | NA | NR | Yes |
Seki T | 2009 | 35 | 100 | Yes | Lauren, Nakamura | 60 | 97 | NA | NA | NR | No |
Ilhan O | 2010 | 19 | 7 | No | WHOc, Lauren | 95 | 11 | NA | NA | NS | Yes |
Bartley AN | 2011 | 22 | 100 | Yes | WHOb | 57 | 100 | NA | NA | NR | No |
Yonezawa S | 2012 | 69 | 35 | No | JGCA | NA | NA | NA | 6 to 97e | No | Yes |
Konno-Shimizu M | 2013 | 51 | 43 | Yes | No | NA | High | NA | NA | NR | No |
Terada T (II) | 2013 | 30 | 100 | Yes | WHOd | 13 | 67 | 70 | 10 (MUC1) | NR | No |
Terada T (III) | 2013 | 30 | 100 | Yes | WHOd | NA | NA | NA | 57 (EMA) | NR | No |
Nakajima T | 2016 | 35 | 100 | No | No | 54 | 94 | 77 | NA | No | No |
Fujimoto A | 2017 | 12 | 12 | No | JGCA | 50 | 75 | NA | NA | NR | Yes |
Kim YH | 2017 | 317f | 100 | Yes | WHOc | 36 | 50 | 44 | NA | NR | No |
Xiong ZF | 2017 | 163 | 100 | Yes | No | 47 | 74 | 29 | 21 | Yes | No |
n number of cases, % percentage of all cases, NA not applicable, NR not reported, NS not specific for SRC, SRC signet-ring cell, GC gastric cancer, WHO World Health Organisation, JGCA Japanese Gastric Cancer Association
aPercentage rounded up
b2nd edition WHO
c3rd edition WHO
d4th edition WHO
eUsed different antibodies
f92 instead of 317 cases were used for immunohistochemistry