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. 2020 Jun 2;23(5):765–779. doi: 10.1007/s10120-020-01086-0

Table 2.

Results literature review reporting on individual immunohistochemical mucin stains

Author Year Number SRC-GC Description SRC-GC Classification tumour type used Mucin stains (% positivea) Relationship with survival Comparison with other tumour types
n % MUC2 MUC5AC MUC6 EMA/MUC1 Yes/No
Sakamoto H 1997 38 17 No No 66 NA NA 7 Yes Yes
Baldus SE 1998 62 48 No WHOb, Lauren 27 NA NA 60/45 Yes Yes
Gürbüz Y 2002 31 19 Yes No 81 100 35 52 NR Yes
Akyürek N 2002 37 26 No Borrmann, WHOc, Lauren 41 NA NA 43 NS Yes
Aihara R 2004 69 100 Yes WHOb, JGCA 41 100 38 NA Yes No
Chu PG 2004 30 100 Yes No 50 50 NA 17 NR No
Zhang HK 2004 31 33 No no 81 55 71 NA NS Yes
Nguyen MD 2006 21 100 Yes No 48 38 29 24 NR No
Sentani K 2008 21 100 Yes No 71 48 NA NA NR No
Chiaravalli AM 2009 24 20 Yes Own 60 60 NA NA NR Yes
Seki T 2009 35 100 Yes Lauren, Nakamura 60 97 NA NA NR No
Ilhan O 2010 19 7 No WHOc, Lauren 95 11 NA NA NS Yes
Bartley AN 2011 22 100 Yes WHOb 57 100 NA NA NR No
Yonezawa S 2012 69 35 No JGCA NA NA NA 6 to 97e No Yes
Konno-Shimizu M 2013 51 43 Yes No NA High NA NA NR No
Terada T (II) 2013 30 100 Yes WHOd 13 67 70 10 (MUC1) NR No
Terada T (III) 2013 30 100 Yes WHOd NA NA NA 57 (EMA) NR No
Nakajima T 2016 35 100 No No 54 94 77 NA No No
Fujimoto A 2017 12 12 No JGCA 50 75 NA NA NR Yes
Kim YH 2017 317f 100 Yes WHOc 36 50 44 NA NR No
Xiong ZF 2017 163 100 Yes No 47 74 29 21 Yes No

n number of cases, % percentage of all cases, NA not applicable, NR not reported, NS not specific for SRC, SRC signet-ring cell, GC gastric cancer, WHO World Health Organisation, JGCA Japanese Gastric Cancer Association

aPercentage rounded up

b2nd edition WHO

c3rd edition WHO

d4th edition WHO

eUsed different antibodies

f92 instead of 317 cases were used for immunohistochemistry