Figure 1.

Genomic deletion analysis of SARS-CoV-2. Genomic deletion analysis of SARS-CoV-2 strains identified (a) 24 (nt) deletions in NSP1 in a Japanese strain; (b) 15-nt deletions in NSP1 of viral strains from USA, Japan and the Netherlands alongside three-nt deletions in USA and Netherlands; (c) three-nt deletion in NSP1 of American strains and very adjacent to that, nine-nucleotide deletion of strains from the USA, England and Canada and Iceland; (d) three-nucleotide deletions in NSP2 were observed in 99 strains from Netherlands, England, Portugal, Slovakia, Iceland, Wales, France and New Zealand (representatives from each countries were shown); (e) NSP8 undergoes three-nt deletion in Netherlandian/dutch/hollanders strains; (f) three-nucleotide deletion in NSP15 of USA strain; (g-g1) 35nt deletion, including start codon position of ORF10 of Spain strains, and the start codon in spacer position, has been used for ORF10 coding; and as a result, (g-g2) five aa residues deletion in those strains starting from position 1 to 5. Deletion of (h) 29-nt reported from Wuhan, and (i) 10-nt in 3′-UTR of strains belonged to Australia. The position of nt represents the starting position from each ORFs, for instance, position of ORF1ab was considered for the NSPs. MAFFT online tool³⁶ was used for alignment, and Unipro-UGENE⁴⁰ used for visualization.