Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 20;11(8):663. doi: 10.1038/s41419-020-02907-x

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 2 — a Expression of EpCAM mRNA in HNSCC patients’ cisplatin resistant and sensitive tumor cells. b Dose-response and cell viability of HNSCC patient tumor cells (top panel), SCC15 (middle panel), and FaDu (bottom panel) cells. Cell viability of siEpCAM and scrambled siRNA transfected cells were monitored following exposures of cells to different concentrations of cisplatin. c EC50 of cisplatin in parental, si-scrambled, and siEpCAM transfected patient tumor cells (top panel), SCC15 (middle panel), and FaDu (bottom panel) cells. The EC50 differences between si-scramble and siEpCAM cells were compared. d Relative EpCAM mRNA expression in HNSCC patient tumor cells (top panel), SCC15 (middle panel), and FaDu (bottom panel) cells following transfection of cells by si-scrambled and siEpCAM. p-values were calculated using Student’s t test. e Cell proliferation was determined following transfection of cells by si-scrambled and siEpCAM. Si-scrambled and siEpCAM cell growth was compared on day 5. ns denote not significant, *p < 0.05, **p < 0.01, ***p < 0.001.