Table 1:

Characteristics of participants and HIV transmission risk behaviors, stratified by willingness to use LAI-PrEP (Bivariate associations; N=234).

Variables	Entire Sample (N = 234)			Willingness to use LAI-PrEPe		OR f (95% CI g)	p
	Frequency		%	No (n = 62)	Yes (n = 172)
Characteristics of participants
Age: Mean (±SD), years a		42.7 (±10.2)		41.5 (±10.6)	43.1 (±10.0)	1.016 (0.987, 1.046)	0.283
Sex
Male		119	50.9	40 (17.1)	79 (33.8)	-	-
Female		115	49.1	22 (9.4)	93 (39.7)	2.140 (1.174, 3.902)	0.013
Heterosexual sexual orientation
No		49	20.9	12 (5.1)	37 (15.8)	-	-
Yes		185	79.1	50 (21.4)	135 (57.7)	0.876 (0.423, 1.803)	0.721
Ethnicity
Non-White		86	36.8	22 (9.4)	64 (27.4)	-	-
White		148	63.2	40 (17.1)	108 (46.2)	0.928 (0.507, 1.700)	0.809
Currently married/living with partner
No		183	78.2	46 (19.7)	137 (58.5)	-	-
Yes		51	21.8	16 (6.8)	35 (15.0)	0.734 (0.372, 1.449)	0.373
High school graduate
No		65	27.8	16 (6.8)	49 (20.9)	-	-
Yes		169	72.2	46 (19.7)	123 (52.6)	0.873 (0.452, 1.686)	0.686
Employed
No		205	87.6	52 (22.2)	153 (65.4)	-	-
Yes		29	12.4	10 (4.3)	19 (8.1)	0.646 (0.282, 1.478)	0.300
Income level
< $10,000		68	29.1	18 (7.7)	50 (21.4)	-	-
≥ $10,000		166	70.9	44 (18.8)	1 22 (54.1)	0.998 (0.527, 1.892)	0.996
Homelessb
No		103	44.0	26 (11.1)	77 (32.9)	-	-
Yes		131	56.0	36 (15.4)	95 (40.6)	0.891 (0.495, 1.603)	0.700
Visited healthcare providerb
No		27	11.5	12 (5.1)	15 (6.4)	-	-
Yes		207	88.5	50 (21.4)	157 (67.1)	2.512 (1.103, 5.721)	0.028
Methadone Dose (mg): Mean (±SD) a		81.9 (±30.5)		86.9 (±31.2)	80.0 (±30.2)	0.992 (0.983, 1.002)	0.129
Moderate to severe depression
No		60	25.6	16 (6.8)	44 (18.8)	-	-
Yes		174	74.4	46 (19.7)	128 (54.7)	1.012 (0.521, 1.966)	0.972
Alcohol use disorder
No		161	68.8	45 (19.2)	116 (49.6)	-	-
Yes		73	31.2	17 (7.3)	56 (23.9)	1.278 (0.672, 2.430)	0.455
HIV transmission risk behaviors
Duration of drug use: Mean (±SD a) years		18.4 (±10.1)		18.3 (±10.3)	18.4 (±10.1)	1.001 (0.973, 1.031)	0.926
Used illicit drug c
No		74	31.6	22 (9.4)	52 (22.2)	-	-
Yes		160	68.4	40 (17.1)	120 (51.3)	1.269 (0.687, 2.344)	0.446
Injected any illicit drug c	n = 160
No		55	23.5	15 (9.4)	40 (25.0)	-	-
Yes		105	44.9	25 (15.6)	80 (80 (50.0)	1.200 (0.570, 2.526)	0.631
Shared injection equipment c	n = 105
No		62	26.5	15 (14.3)	47 (44.8)	-	-
Yes		43	18.4	10 (9.5)	33 (31.4)	1.053 (0.422, 2.631)	0.912
Engaged in sexual intercourse c
No		67	28.6	18 (7.7)	49 (20.9)	-	-
Yes		167	71.4	44 (18.8)	123 (52.6)	1.027 (0.541, 1.949)	0.935
Multiple sex partner c	n = 167
No		75	32.1	23 (13.8)	52 (31.1)	-	-
Yes		92	39.3	21 (12.6)	71 (42.5)	1.495 (0.749, 2.985)	0.254
Consistent condom use c	n = 167
No		153	65.4	41 (24.6)	112 (67.1)	-	-
Yes		14	6.0	3 (1.8)	11 (6.6)	1.342 (0.356, 5.054)	0.663
Engaged in transactional sex c	n = 167
No		121	51.7	36 (21.6)	85 (50.9)	-	-
Yes		46	19.7	8 (4.8)	38 (22.8)	2.012 (0.854, 4.736)	0.110
Sex under the influence of alcohol c	n = 167
No		94	40.2	29 (17.4)	65 (38.9)	-	-
Yes		73	31.2	15 (9.0)	58 (34.7)	1.725 (0.842, 3.533)	0.136
Perceived risk of HIV transmission
Low		175	74.8	54 (23.1)	121 (51.7)	-	-
High		59	25.2	8 (3.4)	51 (21.8)	2.845 (1.264, 6.404)	0.012
Satisfied with current method of HIV prevention
No		89	38.0	22 (9.4)	67 (28.6)	-	-
Yes		145	62.0	40 (17.1)	105 (44.9)	0.862 (0.471, 1.577)	0.630
PrEP-specific variablesd
Heard of oral PrEP
No		77	32.9	28 (12.0)	49 (20.9)	-	-
Yes		157	67.1	34 (14.5)	123 (52.6)	2.067 (1.135, 3.766)	0.018
Ever used oral PrEP
No		174	32.9	56 (23.9)	118 (50.4)	-	-
Yes		60	25.6	6 (2.6)	54 (23.1)	4.271 (1.734, 10.520)	0.002
Heard of LAI-PrEP e
No		174	74.4	50 (21.4)	124 (53.0)	-	-
Yes		60	25.6	12 (5.1)	48 (20.5)	1.613 (0.791, 3.290)	0.189

Note:

^aSD: standard deviation;

^bin the past 12 months;

^cin the past 30 days;

^dPrEP: pre-exposure prophylaxis;

^eLAI-PrEP: long-acting injectable PrEP;

^fodds ratio;

^gconfidence interval