Table 3.

Study 2 (dual infection with bovine coronavirus [BoCV] strain OK 1776 and bovine viral diarrhea virus [BVDV] genotype 2, subgenotype a).

Group	BoCV			BVDV			Lung lesions	Mean highest temperature (°C)
	VI		VN	VI		VN
	BC	NS		BC	NS
2A (BoCV only)	0/2	1/2: d 2,4,6 post-BoCV exposure	1/2: d 9 post-BoCV exposure	0/2	0/2	0/2	0/2	39.1 ± 0.6
2B (BoCV followed 3 d later by BVDV)	0/3	1/3: d 2,4 post-BoCV exposure 2/3: d 2,4,6 post-BoCV exposure	1/3: d 6 post-BoCV exposure 2/3: d 9 post-BoCV exposure	1/3: d 5,7 post-BVDV exposure 2/3: d 5,7,9 post-BVDV exposure	1/3: d 5,7,9 post-BVDV exposure 1/3: d 7,9 post-BVDV exposure 1/3: d 5.7,9,11 post-BVDV exposure	3/3: d 13 post-BVDV exposure	3/3	40.0 ± 0.5
2C (BVDV followed 3 d later by BoCV)	0/3	1/3: d 2,5 post-BoCV exposure 1/3: d 2,5,7 post-BoCV exposure 1/3: d 5,7,9 post-BoCV exposure	3/3: d 13 BoCV exposure	1/3: d 4,6,9 post-BVDV exposure 2/3: d 4,6 post-BVDV exposure	0/3	1/3: d 13 post-BVDV exposure 2/3: d 17 post-BVDV exposure	1/3	40.3 ± 0.8
2D (no virus)	0/2	0/2	0/2	0/2	0/2	0/2	0/2	39.2 ± 0.3

BC = buffy coat; NS = nasal swab; VI = virus isolation; VN = virus neutralization.