Table 1.
Correlation analysis between overall survival and stromal scores or immune scores in 20 different tumor types.
| Cancer type | Low N | High N | Stromal score | Immune score | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Low MST | High MST | HR (95% CI) | p-Value# | Low MST | High MST | HR (95% CI) | p-Value# | |||
| BLCA | 202 | 202 | 1,348 | 859 | 0.77 (0.58–1.04) | 0.0864 | 1,036 | 1,005 | 1.02 (0.76–1.37) | 0.8877 |
| BRCA | 542 | 543 | 3,941 | 3,669 | 1.07 (0.78–1.48) | 0.2648 | 3,736 | 3,959 | 1.41 (1.03–1.93) | 0.0351* |
| CESC | 146 | 147 | 3,046 | 3,097 | 1.16 (0.73–1.84) | 0.5291 | 4,086 | 3046 | 1.50 (0.94–2.37) | 0.0886 |
| COAD | 124 | 125 | Undefined | 2,134 | 1.02 (0.56–1.86) | 0.9391 | Undefined | 2,134 | 1.00 (0.55–1.81) | 0.9956 |
| ESCA | 92 | 93 | 855 | 681 | 0.85 (0.54–1.33) | 0.4791 | 801 | 694 | 0.86 (0.55–1.35) | 0.5168 |
| GBM | 82 | 82 | 442 | 380 | 0.84 (0.58–1.17) | 0.2883* | 427 | 375 | 0.92 (0.65–1.31) | 0.6488 |
| HNSC | 259 | 260 | 1,504 | 1,838 | 1.03 (0.79–1.34) | 0.8338 | 1,430 | 1,762 | 1.21 (0.93–1.58) | 0.1615 |
| KIRC | 266 | 266 | 3,554 | 2,256 | 0.81 (0.60–1.09) | 0.1616 | Undefined | 2,343 | 0.67 (0.50–0.91) | 0.0090** |
| KIRP | 144 | 144 | Undefined | 2,941 | 0.70 (0.39–1.26) | 0.2306 | Undefined | Undefined | 1.26 (0.70–2.28) | 0.4408 |
| LIHC | 183 | 184 | 2,486 | 1,694 | 1.14 (0.81–1.61) | 0.4583 | 1,791 | 1,685 | 1.13 (0.80–1.59) | 0.4990 |
| LGG | 262 | 263 | 4,068 | 2,235 | 0.60 (0.43–0.85) | 0.0036** | 2,907 | 2,052 | 0.65 (0.46–0.92) | 0.0145* |
| LUAD | 252 | 253 | 1,293 | 1,830 | 1.32 (0.99–1.77) | 0.0599 | 1,235 | 1,725 | 1.45 (1.09–1.94) | 0.0124* |
| LUSC | 247 | 247 | 1,695 | 1,470 | 0.88 (0.68–1.16) | 0.3524 | 1,695 | 1,655 | 0.95 (0.72–1.26) | 0.7398 |
| SKCM | 230 | 230 | 2,030 | 2,927 | 1.31 (1.02–1.73) | 0.0409* | 1,860 | 3,259 | 1.69 (1.30–2.21) | 0.0001*** |
| OV | 231 | 232 | 1,359 | 1,324 | 0.94 (0.75–1.18) | 0.5784 | 1,334 | 1,399 | 1.09 (0.87–1.37) | 0.4474 |
| PAAD | 89 | 89 | 634 | 603 | 0.92 (0.61– 1.37) | 0.6703 | 627 | 603 | 1.01 (0.67–1.51) | 0.9801 |
| PCPG | 91 | 91 | Undefined | Undefined | 2.94 (0.67–10.78) | 0.1632 | Undefined | Undefined | 1.41 (0.35–5.70) | 0.6291 |
| PRAD | 248 | 249 | Undefined | Undefined | 2.20 (0.65–7.73) | 0.2221 | Undefined | Undefined | 1.39 (0.40–4.81) | 0.6035 |
| STAD | 194 | 194 | 1,686 | 794 | 0.70 (0.51–0.96) | 0.0285* | 1,043 | 940 | 0.87 (0.65–1.19) | 0.3947 |
| THCA | 254 | 254 | Undefined | Undefined | 1.03 (0.39–2.74) | 0.9527 | Undefined | Undefined | 1.00 (0.37–2.66) | 0.9962 |
#
p-values and HR were calculated by applying the log-rank test; N, number; MST, median survival time; HR, hazard ratio; undefined, the cumulative survival was not <50%;
*
p-value < 0.05;
**
p-value < 0.01;
***
p-value < 0.001.