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. 2020 Aug 11;8:594. doi: 10.3389/fchem.2020.00594

Table 2.

Comparative summary of various sensing platforms reported in literature for calcium ion detection.

Sensing element Sensor type Limit of detection References
Calmodulin (CaM) Fiber-optic sensor 5 × 10−8 M Blair et al., 1994
Carboxylic polyether antibiotic A23187 Fiber-optic sensor 1 × 10−7 M Suzuki et al., 1989
Ionophore N,N,N′,N′-tetracyclohexyl-3-oxapentanediamide Calcium-selective electrode 100 pM Schefer et al., 1986
Sensing membrane consisting of modified merocyanine photoacid polymer and a calcium ionophore in plasticized poly(vinyl chloride) Optical sensor 5 × 10−4 M Johns et al., 2014
NiCo2O4 nanostructures on 3-dimensional graphene foam Electrochemical sensor 4.45 μM Wu et al., 2015
α-Furildioxime ionophore Potentiometric sensor 1.25 × 10−7 M Singh and Mehtab, 2007
Arsenazo III (1,8-dihydroxynaphthalene-3,6-disulfonic acid-2,7-bis[(azo-2)-phenyl arsenic acid]) Microfluidic fiber-optic sensor 2.68 × 10−5 M Caglar et al., 2006
2-[(2-Hydroxyphenyl)imino]-1,2-diphenylethanone (HD) Potentiometric sensor 8.0 × 10−7 M Ganjali et al., 2005
Ethylenediaminetetraacetic acid (EDTA)-carbon dots Optical sensor 77 pM Ankireddy and Kim, 2018
Hexametaphosphate-capped CdS QDs Optical sensor 4 μM Liu et al., 2016
4,4′,4′′,4′′′-((3,6-Dicyanobenzene-1,2,4,5-tetrayl)tetrakis(sulfanediyl))tetra-benzoic acid Optical sensor 0.6 μM Chen et al., 2019
DNA aptamer Optical sensor 3.77 pM This work