Table 1.
Demographic characteristics and initial clinical manifestations of patients with COVID-19 in Wuhan.
|
Clinical characteristics and symptoms |
All patients (n = 121) | Disease severity | χ2 | P-value | Clinical outcomes | χ2 | P-value | ||
|---|---|---|---|---|---|---|---|---|---|
|
Non-severe (n = 69) |
Severe (n = 52) |
Survival (n = 107) |
Death (n = 14) |
||||||
| Age, Median (IQR)—yrs | 65.0 (55.0–71.5) | 60.0 (52.0–68.0) | 69.5 (61.5–79.75) | <0.001a | 64.0 (55.0–70.0) | 67.5 (56.75–79.50) | 0.229a | ||
| Age groups—No., % | |||||||||
| <65 | 63 (52.1) | 46 (66.7) | 17 (32.7) | 13.714 | <0.001 | 58 (54.2) | 5 (35.7) | 1.696 | 0.193 |
| ≥65 | 58 (47.9) | 23 (33.3) | 35 (67.3) | 49 (45.8) | 9 (64.3) | ||||
| Gender—No., % | |||||||||
| Male | 66 (54.5) | 34 (49.3) | 32 (61.5) | 1.799 | 0.180 | 57 (53.3) | 9 (64.3) | 0.606 | 0.436 |
| Female | 55 (45.5) | 35 (50.7) | 20 (38.5) | 50 (46.7) | 5 (35.7) | ||||
| Symptoms—No., % | |||||||||
| Fever on the first admission | 95 (78.5) | 57 (82.6) | 38 (73.1) | 1.597 | 0.206 | 84 (78.5) | 11 (78.6) | 1b | |
| Chest distress | 34 (28.1) | 19 (27.5) | 15 (28.8) | 0.025 | 0.874 | 29 (27.1) | 5 (35.7) | 0.534b | |
| Fatigue | 44 (36.4) | 26 (37.7) | 18 (34.6) | 0.120 | 0.729 | 38 (35.5) | 6 (42.9) | 0.288 | 0.591 |
| Respiratory symptoms | 94 (77.7) | 54 (78.3) | 40 (76.9) | 0.031 | 0.861 | 81 (75.7) | 13 (92.9) | 2.102 | 0.147 |
| Gastrointestinal symptoms | 28 (23.1) | 16 (23.2) | 12 (23.1) | <0.001 | 0.989 | 25 (23.4) | 3 (21.4) | 1b | |
| Neurological symptoms | 12 (9.9) | 6 (8.7) | 6 (11.5) | 0.268 | 0.605 | 9 (8.4) | 3 (21.4) | 0.144b | |
| Coexisting disorders—No., % | |||||||||
| Any | 85 (70.2) | 39 (56.5) | 52 (88.5) | 14.474 | <0.001 | 72 (67.3) | 13 (92.9) | 0.062b | |
| Hypertension | 49 (40.5) | 22 (31.9) | 27 (51.9) | 4.942 | 0.026 | 40 (37.4) | 9 (64.3) | 3.781 | 0.054 |
| Diabetes | 25 (20.7) | 12 (17.4) | 13 (25.0) | 1.047 | 0.306 | 21 (19.6) | 4 (28.6) | 0.484b | |
| Cardiovascular and cerebrovascular | 27 (22.3) | 7 (10.1) | 20 (38.5) | 13.716 | <0.001 | 23 (21.5) | 4 (28.6) | 0.512b | |
| diseases | |||||||||
| Cancer* | 10 (8.3) | 7 (10.1) | 3 (5.8) | 0.749 | 0.387 | 9 (8.4) | 1 (7.1) | 1b | |
| Chronic pulmonary disease∮ | 19 (15.7) | 6 (8.7) | 13 (25.0) | 5.955 | 0.015 | 15 (14.0) | 4 (28.6) | 0.232b | |
Data are presented as medians (interquartile ranges, IQR) and N (%).
P-value denoted the comparison between different groups.
a
Mann-Whitney-Wilcoxon was used for continuous variables.
b
Fisher's exact test.
*
Cancers referred to any malignancy. All cases were stable disease.
∮
Chronic pulmonary disease includes tuberculosis, Chronic obstructive pulmonary disease and Bronchiectasis. All cases were stable and no obvious bacterial infections.