FIGURE 5.

(A–E) Absolute volume of regions affected by diet assessed using a two-way analysis of variance including BMOS, HMO, and their interaction. In each case, (except C) an interaction effect was observed wherein pigs fed the CON or BMOS + HMO diet displayed similar absolute volumes compared to pigs fed either BMOS or HMO. (F–K) Relative volumes of regions affected by diet. (F,G) A main effect of HMO was seen for both the left and right cortices, pigs fed any diet containing HMO demonstrating larger relative cortices. (H) Pigs fed diets containing HMO had a larger relative corpus callosum, whereas pigs fed diets containing BMO had a smaller relative corpus callosum. (I–K) Similar to the effects seen for absolute volumes, interactions effects of diet for relative volumes of the caudate, lateral ventricle, and pons were observed, wherein pigs fed the CON or BMOS + HMO diet displayed similar relative volumes compared to pigs fed either BMOS or HMO.