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. 2020 Aug 7;11:536. doi: 10.3389/fendo.2020.00536

Table 1.

Clinical and epidemiologic characteristics of the oral bone metabolic dysregulation associated with diabetes.

Authors Types of diabetes Number of cases Principal findings
Meenawat et al. (25) T1DM 28 The severity of gingivitis and periodontitis in T1DM patients is significantly higher than that in healthy people.
Puttaswamy et al. (26) T2DM T2DM: 60; Healthy people: 40 The salivary glucose concentration in diabetic patients is significantly higher than that in healthy people, and periodontal status is poorer.
Liljestrand et al. (27) T2DM 8,446 The risk of T2DM in patients with moderate-to-severe periodontitis is 3.2 times higher than that in patients with mild or moderate periodontitis.
Al Zahrani et al. (28) T2DM Well-controlled: 35; Poorly controlled: 32 Patients with poorly controlled T2DM demonstrate worse peri-implant bone outcomes than patients with well-controlled T2DM.
Hong et al. (29) T1DM and T2DM 4,473 43.7% of people with diabetes have periodontitis compared with only 25.0% of the general population.
Annibali et al. (30) T1DM and T2DM Implants: 1,142 Patients with diabetes are more likely to suffer implant failure during the period of osseointegration and the first year of loading.