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. 2020 Aug 4;11:984. doi: 10.3389/fphys.2020.00984

TABLE 1.

Comorbidities associated with COVID-19 related hospitalized cases and deaths.

Conditions Countries
Italy
France
Netherlands
Sweden
Spain
Hosp Death P value Hosp Death P value Hosp Death P value Hosp Death P value Hosp Death P value
N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%) N (%)
Heart Diseases Cardiovascular diseases 219 (21) 1568 (77) <0.0001 612 (19) 118 (33) <0.0001 2635 (48) 874 (50) 0.1468 389 (34) 596 (54) <0.0001 19565 (36) 6650 (53) <0.0001
Hypertension 511 (49) 1410 (69) <0.0001 202 (35*) 11 (26*) 0.231# NA NA 426 (37) NA NA NA NA
Diabetes 177 (17) 647 (32) <0.0001 797 (25) 112 (31) 0.0134 1258 (23) 413 (24) 0.3906# 279 (24) 277 (25) 0.5814# 10239 (19) 3458 (27) <0.0001
Chronic lung diseases 41 (4) 460 (23) <0.0001 515 (16) 84 (23) 0.0007 1342 (25) 419 (24) 0.4008# 162 (14) 191 (17) 0.0492 6439 (12) 2165 (17) <0.0001
Kidney diseases 31 (3) 431 (21) <0.0001 181 (6) 35 (10) 0.0033 414 (8) 185 (11) 0.0001 38 (3) 187 (17) <0.0001 NA NA
Liver diseases 31 (3) 81 (4) 0.1619# 6 (1*) 0 (0*) - 65 (1) 15 (1) 1 8 (1) 13 (1) 1 NA NA
Immunodeficiency NA 5 (0.20) 200 (6) 32 (9) 0.0264 84 (2) 16 (1) 0.0058 61 (5) 59 (5) 1 NA NA
Neurological diseases NA 307 (15) 102 (3) 24 (7) 0.0001 273 (5) 216 (13) <0.0001 12 (1) NA NA NA
Total comorbidity associated hospitalized cases/deaths 1043 2041 3192 OR 578* 360 OR 43* - 5462 1732 1141 1109 55039 12642

The table represents country-wise COVID-19 patients with associated comorbidities in numbers (N) as well as percentage (%). All the percentage values are rounded up. One patient may belong to several other groups. For France, Italy, and Sweden the hospitalized patients’ data was available and considered for intensive care unit (ICU) patients only. While for Spain the hospitalized plus ICU patients and for Netherlands patients admitted in hospital was considered in the category of hospitalized patients. The count of patients with other than enlisted comorbidities presented in the original reports have not been included in the table but considered in the total. NA, Not available; Hosp., Hospitalized patients. (Timespan for country wise data: Italy- Hosp.-NA, death- 21/02/2020–23/04/2020; France- 16/03/2020–21/04/2020; France comorbidities data collected from 04/04/2020 (578 cases including 43 deaths); Spain-31/01/2020–22/04/2020; Netherlands-27/02/2020–10/04/2020; Sweden- 13/04/2020–19/04/2020). Neurological disease = Neuromuscular + neurovascular diseases; Cardiovascular disease = Ischemic heart disease + Atrial fibrillation + Heart failure + Stroke (Italy); Chronic lung disease = respiratory disease (spain)/ pulmonary disease (France); Immunodeficiency = HIV (Italy), Neurological disease = Dementia (Italy). #p > 0.05-not significant; p < 0.05-significant calculated from t-Test two-tailed.