Figure 6.

Prenatal poly I:C treatment lowered the action potential threshold of pyramidal cells in the neonatal period. (A) Representative traces showing action potentials elicited by the rheobase current injection. Each arrow head indicates the estimated threshold voltage for action potential generation. In each traces, 0 mV level in membrane potential is shown as a horizontal dotted line. (B) There was a significant difference in action potential threshold between PBS-treated and poly I:C-treated mice, *p < 0.05. Data are presented as means, and error bars indicate SEM. Poly I:C, polyriboinosinic-polyribocytidilic acid; PBS, phosphate-buffered saline.