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. 2020 Jul 29;11:1130. doi: 10.3389/fphar.2020.01130

Table 3.

Factors influencing overall survival according to the Cox analysis.

Variables HR (95% CI) P
AFP (ng/ml)
 <400 1.000
 ≥400 1.317 (0.772–2.401) 0.369
BCLC stage
 A 1.000
 B 2.097 (0.791–5.558) 0.137
 C 2.108 (0.865–5.137) 0.101
Tumor number
 Single 1.000
 Multiple 1.385 (0.768-2.498) 0.279
Growth pattern
 Non-infiltrative 1.000
 Infiltrative 1.555 (0.743–3.255) 0.241
Vascular invasion
 Absent 1.000
 Present 1.259 (0.701–2.262) 0.441
Therapy
 TACE-sorafenib-thermal ablation 1.000
 TACE-sorafenib 2.512 (1.348–4.680) 0.004

Multivariate analysis was not performed because only the choice of treatment had a P-value <0.05 in univariable analyses. HBV status and Child-Pugh grades could not be analyzed because of the too small number of patients in some categories.