TABLE 1.

A selective overview of studies reporting exosomes in Sjögren’s syndrome.

Articles	Origin of exosomes	Exosome components	Role in pathology	As a biomarker	Potent therapeutic effect
(88)	SGECs		+
(89)	B cells	ebv-miR-BART13-3p	+
(90)	T cells	miR-142-3p	+
(93)	SGECs, lacrimal gland cells			+
(94)	SGECs	miRNAs		+
(95)	SGECs	miRNAs		+
(96)	DCs				+
(97)	DCs				+
(98)	MSCs				+
(100)	Placenta tissue	miRNAs of C19MC			+
(87)	human umbilical cord MSCs				+

SGECs, salivary gland epithelial cells; DCs, dendritic cells; MSCs, mesenchymal stem cells; miRNA, microRNA; C19MC, chromosome 19 microRNA cluste.