Table 1.

Normalized respiratory flux control ratios.

Normalized respiratory flux ratios	H9c2 cells treatment
	Control	Pin	Dox	Dox + Dex	Dox + Pin
State apparent	3.60±0.01	3.49±0.02	3.23±0.05###	3.20±0.09##	3.38±0.02*
Respiratory control ratio (RCR)	39.27±3.94	33.67±1.84**	15.85±2.64##	15.44±1.98###	23.85±3.27##
Coupling efficiency	0.93±0.01	0.91±0.02***	0.82±0.01###	0.87±0.01##	0.88±0.01*

The state _apparent, respiratory control ratio (RCR) and coupling efficiency of H9c2 cells in the presence or absence of Dox, Pin, Dox plus Pin and Dox plus Dex were derived from the mitochondrial parameters presented in Figure 5. Data represents mean ± SEM; n=6. Significance is indicated as ^##p ≤ 0.01, ^###p ≤ 0.001 versus the control; ^*p ≤ 0.05, ^**p ≤ 0.01, ^***p ≤ 0.001 versus Dox.