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. 2020 Jul 31;11:1150. doi: 10.3389/fphar.2020.01150

Figure 4.

Figure 4

Upregulation of cardiac production of myocardial collagen fibers, type III collagen in STZ-injected rat in vivo, This effect can be antagonized by hydrogen sulfide (A) Representative images of masson with a myocardial collagen fibers in the heart tissues of STZ-injected rat models. Images were acquired at 10×40 magnification. (B) Representative images of VG with a myocardial collagen fibers in the heart tissues of STZ-injected rat models. Images were acquired at 10×40 magnification. (C) Representative images of immunocytochemical with myocardial collagen fibers in the heart tissues of STZ-injected rat models. Images were acquired at 10×40 magnification. (D) Comparison of expression of miR-29 in myocardial tissue treated with Control; STZ; STZ +H2S; H2S; (E) Western blotting analysis the expression of MMP8, MMP13, MMP14 in myocardial tissue treated with Control; STZ; STZ +H2S; H2S; n = 3, *p < 0.05 vs control. **p < 0.01 vs control. #p < 0.05 vs STZ. ##p < 0.01 vs STZ. STZ, streptozotocin; H2S, hydrogen sulfide.