Table 2.
Top ten up- and downregulated genes.
| S.No. | Gene | Gene name | Combined ES | P-value |
|---|---|---|---|---|
| Upregulated genes | ||||
| 1 | CD14 | Monocyte differentiation antigen CD14 | 1.2948 | 4.98E-08 |
| 2 | RPIA | Ribose 5-phosphate isomerase A | 1.1376 | 4.63E-08 |
| 3 | TNFSF11 | Tumor necrosis factor super family member 11 | 1.1229 | 3.66E-08 |
| 4 | PLXND1 | Plexin D1 | 1.1223 | 3.60E-08 |
| 5 | HLA-DMB | Major histo-compatibility complex, class II, DM beta | 1.1168 | 3.97E-08 |
| 6 | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein | 1.1142 | 4.06E-08 |
| 7 | OSBPL3 | Oxysterol binding protein like 3 | 1.1119 | 4.79E-08 |
| 8 | PRAF2 | PRA1 domain family member 2 | 1.1117 | 4.61E-08 |
| 9 | PILRB | Paired immunoglobin like type 2 receptor beta | 1.1078 | 4.67E-08 |
| 10 | RGS16 | Regulator of G protein signaling 16 | 1.1064 | 4.79E-08 |
| Downregulated genes | ||||
| 1 | FUT2 | Fucosyltransferase 2 | -1.1095 | 4.67E-08 |
| 2 | SECISBP2L | SECIS binding protein 2 like | -1.111 | 4.52E-08 |
| 3 | COPS4 | COP9 signalosome subunit 4 | -1.1148 | 4.79E-08 |
| 4 | GSN | Gelsolin | -1.117 | 4.04E-08 |
| 5 | GPX3 | Glutathione peroxidase 3 | -1.1185 | 3.87E-08 |
| 6 | ADH1A | Alcohol dehydrogenase 1A (class I), alpha polypeptide | -1.1271 | 4.39E-08 |
| 7 | CORO2A | Coronin 2A | -1.2074 | 4.67E-08 |
| 8 | ACADS | Acyl-CoA dehydrogenase short chain | -1.2157 | 3.57E-08 |
| 9 | RCAN2 | Regulator of calcineurin 2 | -1.2172 | 5.07E-08 |
| 10 | CLEC3B | C-type lectin domain family 3 member B | -1.2316 | 3.73E-08 |
*Combined ES, Cochran's combination test of random effect model (REM) or effect size (ES).