Table 4.
Bone turnover markers in included studies of patients with congenital adrenal hyperplasia.
| First author and year of publication | CTX (ng/L) | BALP (units/L)a | Osteocalcin (mcg/L) | Urinary NTX/creatinine (nmol/mmol) | ||||
|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | |
| Ceccato 2016 (42) | 380.2+/−166.6 | 331.7+/−208 | 11.1+/−5.4 | 11.2+/−3.8 | NR | NR | NR | NR |
| Falhammar 2007 (36) | <30y:376+/−29 >30y:224+/−23 | <30Y:410+/−30 >30Y: 346+/−21 | NR | NR | NR | NR | NR | NR |
| Falhammar 2013 (37) | 445+/−148 | 455+/−247 | 10.3+/−3.5 | 12.7+/−6.9 | 18.6+/−7 | 25.6+/−8.5 | 53+/−21 | 51+/−34 |
| Guo 1996 (23) | NR | NR | 32 (19–58) | 45 (25–75) | 4 (1–7) | 5.6 (2.8–9) | 32 (10–58) | 58 (30–110) |
| Raizada 2016 (43) | NR | NR | 120 | NR | NR | NR | NR | NR |
| Sciannamblo 2006 (34) | F: 900 (330–1,690) M: 850 (430–1,330) | F:460 (90–1,090) M:600 (310–1,650) | NR | NR | NR | NR | NR | NR |
NR, not reported.
a
Units varied between studies: microg/l(Ceccato 2016), microkat/L(Falhammar 2007,2013), U/L(Guo 1996), IU/L Raizada 2016).