Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 13;14:52. doi: 10.3389/fnana.2020.00052

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Marshall, McClain, Wooden and Nixon.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Ethanol increases the number of dystrophic microglia. Rats exposed to ethanol had more Iba1+ dystrophic microglia in both adolescents (A,B) and adults (E,F) compared with the controls. Arrows in photomicrographs indicate Iba1+ dystrophic microglia as signified by beaded processes and/or cytorrhexis in panels (C,D,G). Although dystrophic cell counts were based on Iba1+ cells, a secondary microglial marker, OX42, also showed the presence of cytorrhexis in 4-day binge ethanol exposed adult rats (D) compared with a normal ramified microglial cell in adult controls (H). Data are mean ± SEM. Scale bar = 20 μm, *p < 0.05.