5.

病例组与对照组的统计关联

Association statistics of the NSCL/P and control panels

SNP	Genotype		Control		NSCL/P		OR (95%CI)		P(OR)		P(Logistic)		P(Bonferroni)		P(HWE)
SNP, single-nucleotide polymorphism; NSCL/P, non-syndromic cleft lip and/or palate; P (Logistic), ajusted with gender; P (Bonferroni), ajus-ted P value by Bonferroni correction; P (HWE), ajusted P value by HWE test; HWE, Hardy-Weinberg equilibrium.
rs12674259	G/G		77 (77%)		61 (62.9%)		1
	G/T		19 (19%)		36 (37.1%)		0.42 (0.22-0.81)		0.0017		0.0016		0.043		0.062
	T/T		4 (4%)		0 (0%)		NA (0.00-NA)
rs7582470		A		G		0.062		0.804		1.054		0.213		0.695-1.599
rs1992900		C		T		0.337		0.561		1.134		0.217		0.742-1.735
rs895479		G		A		0.088		0.767		0.930		0.247		0.573-1.507
rs4848124		C		T		1.851		0.174		1.402		0.249		0.861-2.283
rs277555		C		T		0.375		0.540		1.162		0.246		0.718-1.882
rs277536		A		G		0.000		0.989		1.003		0.225		0.646-1.559
rs1187935		C		A		0.001		0.974		0.992		0.253		0.604-1.628
rs3738880		A		C		0.000		1.000		1.000		0.211		0.661-1.512
rs2718107		A		C		0.347		0.556		0.881		0.215		0.578-1.343
rs4731562		A		G		1.596		0.207		1.336		0.229		0.852-2.093
rs2566871		T		C		0.304		0.581		0.890		0.212		0.587-1.348
rs12674259		T		G		1.527		0.217		0.698		0.292		0.393-1.237
rs9607		A		G		0.450		0.503		0.846		0.250		0.519-1.380
rs4728160		G		C		0.001		0.973		0.992		0.250		0.607-1.619
rs1233560		C		T		1.640		0.200		1.380		0.252		0.842-2.261
rs208684		C		A		0.790		0.374		1.248		0.250		0.765-2.035
rs16909859		A		G		1.489		0.222		0.714		0.277		0.415-1.228
rs357564		G		A		0.479		0.489		0.860		0.218		0.561-1.318
rs2236407		G		A		0.002		0.965		1.010		0.221		0.655-1.558
rs2066836		T		C		0.310		0.578		1.239		0.386		0.581-2.642
rs2277184		G		A		2.396		0.122		1.588		0.300		0.881-2.859
rs2297088		A		G		0.114		0.736		1.077		0.219		0.701-1.653
rs2282041		G		A		1.227		0.268		0.686		0.342		0.351-1.340