Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Aug 13;14:251. doi: 10.3389/fncel.2020.00251

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Zuo, Yin, Cheng, Li, Wu, Liu, Gu and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Elamipretide rescues surgery-induced neuronal damage and synaptic dysfunction in the mouse hippocampus. (A) Representative images of Hematoxylin and Eosin (HE) staining in the hippocampal CA1 region. Scale bar = 25 μm for all photographs. The lower panel shows statistical scores of neuronal damage. (B) Representative images of TUNEL staining in the hippocampal CA1 region. TUNEL-positive cells are dark brown. Scale bar = 50 μm for all photographs. The lower panel presents the number of TUNEL-positive neurons in the CA1 region of the hippocampus. (C) Representative western blotting and quantitative analysis of protein levels of synapsin 1 and PSD-95 in the hippocampus in aged mice. Values are presented as mean ± SEM (n = 6 mice/group). *p < 0.05 vs. the Veh group; ^#p < 0.05 vs. the Sur group.