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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2020 Jun 4;40(8):1870–1890. doi: 10.1161/ATVBAHA.120.314465

Figure 2.

Figure 2.

Characterization of vein graft (VG) remodeling of wild type (WT) jugular veins (JVs) transplanted to the carotid arteries (CAs) in which mature SMCs were genetically labeled with YFP. (A) Schematic presentation of WT JVs grafted into CAs of the reporter mice. Total number of VGs is 12. (B) The Nh index and Lp index of the VGs. VG, all VGs; VG-S, VGs with severe NI formation; VG-M, VGs with mild NI formation. (C) The percentages of SMA, YFP and SMA and YFP double positive cells in each major layer of VGs with two type of VG-remodeling (n=3). Data are means ± SEM. (D) The representative images of co-staining of YFP and SMA as well as co-staining of YFP and CD31 in the cross-sections of #1 segment at the proximal end (Pro), #3–#7 segments at the middle part (Mid), and #9 segment at the distal end (Dis) of VGs. YFP is green; SMA and CD31 are red. L, the lumen; IN, the intima; NI, the neointima; Ad, the adventitia. White dotted lines separate the NI and the Ad layers.