Table 1.
Electrophysiological properties of the PTP and ATP synthase
Preparation | Conductance | Selectivity | Rectification | Reference |
---|---|---|---|---|
PTP | ||||
I MM, patch clamping, induced by cuprizone | ~100pS | Slight anion selectivity | Not determined | Sorgato et al. (1987) |
Mitoplast. patch clamping | Multiple conductances (30 pS to 1.3 nS) | Slight anion selectivity | Positive rectification at positive potentials and negative rectification at negative potentials | Petronilli et al. (1989) |
Mitoplast, patch clamping (mitochondrial muhiconductance channel) | Multiple conductances (10 pS to 1 nS) | Slight cation selectivity | Variable rectification at positive and negative potentials | Kinnally et al. (1989) |
ATP synthase | ||||
ATP synthase dimers in lipid bilayers | Peak conductance of 1-1.3 nS with multiple subconductance states | Not determined | Not determined | Giorgio et al. (2013) |
ATP synthase monomers in liposomes, patch clamping | Multiple conductances (-800 pS) | Not determined | Not determined | Alavian et al. (2014) |
Purified ATP synthase c-subunits in lipid bilayers | Multiple conductances (15 pS to 2 nS) | Relative cation selectivity | Not tested | Azarashvili et al. (2014) |
Purified ATP synthase c-subunits in liposomes, patch clamping | Multiple conductances (lOOpS to 2 nS) | Slight cation selectivity | Slightly negative rectification | Alavian et al. (2014) |