TABLE 1.
Demographics and risk factors in colorectal cancer cases and controls
| Characteristics | Case (N = 315) | Control (N = 441) | P |
|---|---|---|---|
| Age | 63.35 ± 7.33 | 62.50 ± 7.33 | .116 |
| BMI | 25.18 ± 1.45 | 25.15 ± 1.51 | .802 |
| Gender | .816 | ||
| Male | 60 (19.0%) | 87 (19.7%) | |
| Female | 255 (81.0%) | 354 (80.3%) | |
| Smoking | <.001 | ||
| Yes | 204 (64.8%) | 203 (46.0%) | |
| No | 111 (35.2%) | 238 (54.0%) | |
| Alcohol | <.001 | ||
| Yes | 277 (87.9%) | 220 (49.9%) | |
| No | 38 (12.1%) | 221 (50.1%) | |
| Family history | |||
| Yes | 44 (14.0%) | ||
| No | 271 (86.0%) | ||
| Histological grade | |||
| Well differentiated | 32 (10.2%) | ||
| Moderately differentiated | 248 (78.7%) | ||
| Poorly differentiated | 35 (11.1%) | ||
| TNM stage | |||
| I | 67 (21.3%) | ||
| II | 90 (28.6%) | ||
| III | 93 (29.5%) | ||
| IV | 65 (20.6%) | ||
| Tumor size | |||
| >4 cm | 165 (52.4%) | ||
| ≤4 cm | 150 (47.6%) | ||
| Lymph node metastasis | |||
| No | 182 (57.8%) | ||
| Yes | 133 (42.2%) | ||
| Location of colorectal cancer | |||
| Colon cancer | 113 (35.9%) | ||
| Rectal cancer | 202 (64.1%) | ||
| Pathology subtypes | |||
| Adenocarcinoma | 300 (95.1%) | ||
| Squamous cell carcinoma | 13 (4.1%) | ||
| Others | 2 (0.8%) |
Bold values are significant results.
Abbreviations: BMI, body mass index; TNM, tumor node metastasis.