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. 2020 Mar 24;34(8):e23311. doi: 10.1002/jcla.23311

TABLE 3.

Stratified analyses between H19 gene rs2839698 polymorphism and the risk of colorectal cancer

Variable (case/control) GA vs GG AA vs GG AA vs GG + GA AA + GA vs GG
GG GA AA
Sex
Male 30/33 24/44 6/10 0.60 (0.30‐1.21); 0.153 0.66 (0.21‐2.04); 0.470 0.86 (0.29‐2.50); 0.775 0.61 (0.31‐1.19); 0.147
Female 104/121 116/167 34/64 0.81 (0.57‐1.16); 0.251 0.62 (0.38‐1.01); 0.055 0.69 (0.44‐1.09); 0.112 0.76 (0.54‐1.05); 0.104
Smoking
Yes 80/77 101/102 23/24 0.96 (0.63‐1.46); 0.858 0.92 (0.48‐1.77); 0.808 0.94 (0.51‐1.73); 0.849 0.96 (0.64‐1.42); 0.821
No 54/77 39/109 17/50 0.51 (0.31‐0.85); 0.009 0.49 (0.25‐0.93); 0.029 0.68 (0.37‐1.24); 0.211 0.50 (0.32‐0.80); 0.004
Alcohol
Yes 109/83 131/97 36/40 1.04 (0.71‐1.53); 0.847 0.69 (0.40‐1.17); 0.165 0.67 (0.41‐1.10); 0.111 0.94 (0.65‐1.35); 0.718
No 25/71 9/114 4/34 0.22 (0.10‐0.51); 0.001 0.33 (0.11‐1.04); 0.058 0.64 (0.21‐1.92); 0.426 0.25 (0.12‐0.52); 0.001
Age (y)
<60 28/56 36/68 14/23 1.06 (0.58‐1.94); 0.854 1.22 (0.55‐2.72); 0.632 1.18 (0.57‐2.45); 0.658 1.10 (0.62‐1.94); 0.746
≥60 106/98 104/143 26/51 0.68 (0.47‐0.98); 0.041 0.47 (0.27‐0.81); 0.007 0.58 (0.35‐0.97); 0.037 0.62 (0.44‐0.89); 0.009
BMI
<24 28/38 25/43 11/11 0.79 (0.39‐1.58);0.503 1.36 (0.52‐3.57);0.536 1.53 (0.62‐3.78);0.356 0.91 (0.48‐1.73);0.761
≥24 106/116 115/168 29/63 0.75 (0.53‐1.07);0.110 0.50 (0.30‐0.84);0.008 0.59 (0.37‐0.95);0.029 0.68 (0.49‐0.95);0.025

Bold values are statistically significant (P < .05).