Skip to main content
. 2020 Aug 5;5(32):20187–20201. doi: 10.1021/acsomega.0c01867

Scheme 1. Workflow Used to Study the Conformation and Dynamics of RNA Aptamers from the Sequence.

Scheme 1

The approach consists of three main steps, involving RNA 3D structure prediction from the sequence using MC-Fold|MC-Sym pipeline, model selection from the pool of predicted structures and multiple independent MD simulations using selected models as initial structures.