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. 2020 Aug 3;5(32):20399–20408. doi: 10.1021/acsomega.0c02364

Figure 8.

Figure 8

Effect of co-treatment with p38 MAPK activator and ICA on cell viability, barrier function, and oxidative stress in MODE-K cells with BPA challenge. (A) Cells viability and (B) LDH activity of MODE-K cells. (C) TEER and (D) FITC-D4 of MODE-K cells. Changes in the levels of (E) mitochondrial ROS (MitoSOX dye oxidation) and (F) total intracellular ROS (H2DCF oxidation) in MODE-K cells. mRNA expression of (G) ZO-1, (H) occludin, and (I) claudin-1 in MODE-K cells detected by RT-qPCR. Values are the mean ± standard error (n = 6). *p < 0.05 vs CON group; #p < 0.05 vs BPA group.