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. 2020 Jul 22;6(30):eaay9597. doi: 10.1126/sciadv.aay9597

Fig. 3. Arginine catabolic pathway mediated the effect of DCH.

Fig. 3

(A) Proteome changes in MRSA USA300 after DCH treatment using iTRAQ labeling. (B) Thirty-eight COG enrichment differentially expressed proteins were profiled. (C) Ornithine carbamoyltransferase, arginine deiminase, and carbamate kinase were involved in S. aureus arginine catabolic pathway. (D) Expression of arc gene cluster (arcA, arcB, arcC, and arcD) was significantly reduced after DCH treatment at concentrations of 0.25, 0.5, 1, 2, and 4 μg/ml. n = 6; *P < 0.05, **P < 0.01 and ***P < 0.001 versus control (CON).