Table 1. Activity of DCH against pathogenic bacteria.
The MIC was determined by broth microdilution. MSSA, methicillin-susceptible S. aureus; MRSA, methicillin-resistant S. aureus; MDR, multidrug resistant.
| Microorganism | MIC (μg ml−1) |
| G+ bacteria | |
| Staphylococcus aureus (MSSA, ATCC 29213) | 4 |
| Staphylococcus aureus (MRSA, USA300) | 4 |
| Staphylococcus aureus (MRSA, VISA, ATCC 700699) | 4 |
| Staphylococcus aureus (MRSA, clinical strain XJ 75302) | 4 |
| Staphylococcus aureus (MRSA, clinical strain XJ 141240) | 8 |
| Staphylococcus aureus (MRSA, clinical strain XJ 140718) | 4 |
| Staphylococcus epidermidis (ATCC 14990) | 8 |
| Staphylococcus epidermidis (MRSE, clinical strain) | 8 |
| Enterococcus faecalis (ATCC 29212) | 32 |
| Streptococcus pneumoniae (ATCC 49619) | 64 |
| G− bacteria | |
| Escherichia coli (ATCC 25922) | >256 |
| Escherichia coli (MDR, ATCC 35218) | >256 |
| Escherichia coli (MDR, clinical strain XJ 74283) | >256 |
| Enterohemorrhagic Escherichia coli (0157:H7) | >256 |
| Pseudomonas aeruginosa (ATCC 27853) | >256 |
| Pseudomonas aeruginosa (MDR, clinical strain XJ 75315) | >256 |
| Pseudomonas aeruginosa (ΔmexB PAO1 strain) | >256 |
| Pseudomonas aeruginosa (ΔmexN PAO1 strain) | >256 |
| Pseudomonas aeruginosa (ΔmexW PAO1 strain) | >256 |
| Pseudomonas aeruginosa (ΔmuxA PAO1 strain) | >256 |
| Klebsiella pneumoniae(MDR, ATCC 75297) | >256 |
| Acinetobacter baumannii (ATCC 19606) | >256 |
| Acinetobacter baumannii (clinical strain XJ 17014279) | >256 |
| Acinetobacter baumannii (clinical strain XJ 17014346) | >256 |
| Salmonella typhimurium (SL 1344) | >256 |
| Salmonella typhimurium (clinical strain) | >256 |
| Mycobacterium | |
| Mycobacterium smegmatis (ATCC 70084) | 128 |
| Mycobaterium tuberculosis (H37Rv) | 256 |