. 2020 Mar 23;34(8):e23306. doi: 10.1002/jcla.23306

Table 4.

Estimated haplotype frequencies and case‐control haplotype results of the human SOX11 gene

Combinations	Haplotype	Haplotype frequency ^a	χ ²	P	OR (95%CI)	global
SNP2‐SNP3	C‐A T‐A T‐G	518.94 (0.338) 95.06 (0.062) 920.94 (0.600)	999.81 (0.371) 155.19 (0.058) 1537.81 (0.570)	4.683 0.325 3.356	.0305 .5687 .0670	0.87 (0.76‐0.99) 1.08 (0.83‐1.41) 1.13 (0.99‐1.28)	4.711	.0950
SNP5‐SNP6‐ SNP7‐SNP8	A‐G‐A‐A A‐G‐G‐G A‐T‐G‐G G‐T‐G‐G	576.50 (0.376) 126.03 (0.082) 47.62 (0.031) 703.19 (0.458)	889.03 (0.331) 249.09 (0.093) 112.79 (0.042) 1315.78 (0.490)	10.136 1.171 3.028 3.077	.0015 .2793 .0819 .0795	1.24 (1.09‐1.42) 0.88 (0.71‐1.10) 0.74 (0.52‐1.04) 0.89 (0.78‐1.01)	11.941	.0076
SNP9‐SNP10‐ SNP11‐SNP12	A‐G‐A‐C G‐T‐C‐T G‐G‐A‐C	846.14 (0.551) 402.90 (0.262) 253.77 (0.165)	1363.17 (0.506) 817.71 (0.304) 460.74 (0.171)	8.502 7.921 0.207	.0036 .0049 .6492	1.21 (1.06‐1.37) 0.82 (0.71‐0.94) 0.96 (0.81‐1.14)	9.729	.0078
SNP13‐SNP14‐ SNP15	C‐A‐C C‐G‐C C‐G‐T T‐A‐C	252.54 (0.165) 251.76 (0.164) 405.81 (0.265) 608.66 (0.397)	488.28 (0.181) 464.55 (0.172) 734.91 (0.273) 982.62 (0.364)	1.827 0.459 0.314 4.418	.1766 .4980 .5755 .0356	0.89 (0.75‐1.05) 0.94 (0.80‐1.12) 0.96 (0.83‐1.11) 1.15 (1.01‐1.31)	4.852	.1831

Combinations

Haplotype

Haplotype frequency ^a

χ ²

OR (95%CI)

global

Case

Control

χ ²

SNP2‐SNP3

C‐A

T‐A

T‐G

518.94 (0.338)

95.06 (0.062)

920.94 (0.600)

999.81 (0.371)

155.19 (0.058)

1537.81 (0.570)

4.683

0.325

3.356

.0305

.5687

.0670

0.87 (0.76‐0.99)

1.08 (0.83‐1.41)

1.13 (0.99‐1.28)

4.711

.0950

SNP5‐SNP6‐

SNP7‐SNP8

A‐G‐A‐A

A‐G‐G‐G

A‐T‐G‐G

G‐T‐G‐G

576.50 (0.376)

126.03 (0.082)

47.62 (0.031)

703.19 (0.458)

889.03 (0.331)

249.09 (0.093)

112.79 (0.042)

1315.78 (0.490)

10.136

1.171

3.028

3.077

.0015

.2793

.0819

.0795

1.24 (1.09‐1.42)

0.88 (0.71‐1.10)

0.74 (0.52‐1.04)

0.89 (0.78‐1.01)

11.941

.0076

SNP9‐SNP10‐

SNP11‐SNP12

A‐G‐A‐C

G‐T‐C‐T

G‐G‐A‐C

846.14 (0.551)

402.90 (0.262)

253.77 (0.165)

1363.17 (0.506)

817.71 (0.304)

460.74 (0.171)

8.502

7.921

0.207

.0036

.0049

.6492

1.21 (1.06‐1.37)

0.82 (0.71‐0.94)

0.96 (0.81‐1.14)

9.729

.0078

SNP13‐SNP14‐

SNP15

C‐A‐C

C‐G‐C

C‐G‐T

T‐A‐C

252.54 (0.165)

251.76 (0.164)

405.81 (0.265)

608.66 (0.397)

488.28 (0.181)

464.55 (0.172)

734.91 (0.273)

982.62 (0.364)

1.827

0.459

0.314

4.418

.1766

.4980

.5755

.0356

0.89 (0.75‐1.05)

0.94 (0.80‐1.12)

0.96 (0.83‐1.11)

1.15 (1.01‐1.31)

4.852

.1831

Significant P values (<.05) are in boldface.

^{^a}

Frequencies are shown in parenthesis.