FIG 4.
Top recombination events observed among CHIKV 181/clone25 D-RNAs. One replicate of each of intracellular RNA from CHIKV-infected Vero cells collected 12 h post-infection (hpi) (A) and supernatant collected 48 hpi (B) was sequenced and evaluated for defective RNA (D-RNA) expression using ViReMa v1.5. Recombinant count data were normalized to count per 106 CHIKV mapped reads, and the top 80 recombination events were split into insertion-duplication events (top) and deletion events (bottom). Color represents the percentage of overall recombination events represented by a single event.