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Ace2 directly or indirectly represses a large set of genes during hyphal morphogenesis. (A) Volcano plot of the gene expression profiles of ace2ΔΔ cells relative to that of the wild type after 4 h in Spider medium (SM) at 37°C, with genes showing statistically significant (adjusted P < 0.05) changes in expression of ±log2 of 1. (B) Venn diagram of differentially expressed genes (adjusted P < 0.05) for an ace2ΔΔ mutant relative to that of the wild type under yeast-phase and hyphal growth.
