Table 3.

Assessment of the top 15 false-positive trajectories

First disease	ICD-10	Second disease	ICD-10	Assessment
Mental and behavioural disorders due to use of alcohol	F10	Alzheimer’s disease	G30	Described in literature [37]
Essential (primary) Hypertension	I10	Alzheimer’s disease	G30	Described in literature [38]
Osteoporosis without pathological fracture	M81	Alzheimer’s disease	G30	Described in literature [39]
Non-insulin-dependent diabetes mellitus	E11	Alzheimer’s disease	G30	Described in literature [40]
Other disorders of pancreatic internal secretion	E16	Alzheimer’s disease	G30	Described in literature [41]
Schizophrenia	F20	Other septicaemia	A41	Described in literature, but commonly occurs via intermediate diseases such as agranulocytosis and pneumonia [42]
Lupus erythematosus	L93	Other disorders of urinary system	N39	Described in literature [43]
Disorders of vestibular function	H81	Alzheimer’s disease	G30	Described in literature [44]
Lupus erythematosus	L93	Respiratory failure, not elsewhere classified	J96	Described in literature [45]
Unspecified Dementia	F03	Dementia in Alzheimer’s Disease	F00	Further specification of diagnosis
Retinal vascular occlusions	H34	Cystitis	N30	No relationship found in literature
Chronic ischaemic heart disease	I25	Other septicaemia	A41	Cardiac troponins are suggested to be biomarkers for sepsis [46]
Hyperplasia of prostate	N40	Alzheimer’s disease	G30	No relationship found in literature
Hyperparathyroidism and other disorders of parathyroid gland	E21	Alzheimer’s disease	G30	Suggested in literature (via calcium) [47]
Asthma	J45	Umbilical hernia	K42	No relationship found in literature