Fig. 6.

SRSF1-associated exosome miRNA sequence motif analysis. a The motif commonly shared among SRSF1-associated exosome miRNAs. b Venn diagram showing the number of SRSF1-associated exosome miRNAs that share the motif. c List of miRNAs sharing the common motif. d EMSA analysis demonstrating the inhibition of GST-SRSF1 binding to miR-1246 by RNA decoys (D1: decoy 1, 5′-UUGGACUAGGACUAGGAU-3′; D2: decoy 2, 5′-AGGAAGGAAGGAAGGA-3′). e Concentration-dependent inhibition of GST-SRSF1 binding to miR-1246 by D2. f Semi-quantification of the detected bands in Fig. 5e and the calculated dissociation constant