Table 3.
Characteristics of participants who had not undergone surgical sterilization that are statically significantly associated with becoming pregnant during the trial period (n= 94*)
| Participant attribute | Cases (n=26) | Controls (n=68) | OR (95% CI) | p-value |
|---|---|---|---|---|
| Age, years | <0.01 | |||
| Mean ± std | 27 ± 6 | 35 ± 8 | ||
| Range | 19–37 | 19–45 | ||
| Age group | 0.31 (0.11,0.83) | 0.02 | ||
| <30 | 19 (73.1) | 31 (45.6) | ||
| >=30 | 7 (26.9) | 37 (54.4) | ||
| Douches after sex | 2.64 (0.98, 7.15) | 0.05 | ||
| Yes | 10 (38.5) | 13 (19.1) | ||
| No | 16 (61.5) | 55 (80.9) | ||
| Ever had an induced abortion | 2.78 (1.09, 7.10) | 0.03 | ||
| Yes | 13 (50.0) | 18 (26.5) | ||
| No | 13 (50.0) | 50 (73.5) | ||
| Self and partner desire a baby in the future | 5.44 (1.99, 14.89) | <0.01 | ||
| Yes | 16 (66.7) | 18 (26.9) | ||
| No | 8 (33.3) | 49 (73.1) | ||
| Change in contraceptive method while enrolled in HPTN 035 | 3.31 (1.25, 8.72) | 0.01 | ||
| Yes | 12 (46.2) | 14 (20.6) | ||
| No | 14 (53.8) | 54 (79.4) | ||
| HPTN 035 study staff gave information about contraception | 3.24 (1.23, 8.56) | 0.01 | ||
| Yes | 12 (46.2) | 14 (20.9) | ||
| No | 14 (53.8) | 53 (79.1) |
p-values for cells greater than 5 are from chi-square tests and otherwise are from Fisher exact test.
*
A total of 28 controls are excluded from this analysis due to prior surgical sterilization and exceedingly low risk of pregnancy. Three of these controls had been matched to a single case. Fourteen were matched 1:1 to a case and 13 were matched 2:1 to a case.