Table 1.
Characteristic’s patients
| Variable | All patients n = 60 |
PEEPINCREMENTAL n = 30 |
PEEPDECREMENTAL n = 30 |
p value |
|---|---|---|---|---|
| Age | 68 ± 9 | 66 ± 8 | 67 ± 9 | 0.571 |
| BMI | 27.5 ± 5.5 | 27.0 ± 6.2 | 27.8 ± 5.5 | 0.576 |
| ASA score | 0.506 | |||
| II | 11 | 4 | 7 | |
| III | 49 | 26 | 23 | |
| Sex (M/F), n | 40/20 | 18/12 | 22/8 | 0.411 |
| Surgery side (L/R) | 29/31 | 13/17 | 15/15 | 0.312 |
| Type of surgery | 0.061 | |||
| Lobectomy | 55 | 30 | 25 | |
| Wedge resection | 5 | – | 5 | |
| Duration of MV (min) | 212 [175–255] | 218 [195–255] | 205 [175–255] | 0.57 |
| Duration of OLV (min) | 192 [166–240] | 195 [180–240] | 190 [145–240] | 0.49 |
| Comorbidities | ||||
| Diabetes, n (%) | 8 (13) | 4 (13) | 4 (13) | 0.999 |
| Hypertension, n (%) | 35 (50) | 10 (33) | 16 (53) | 0.192 |
| Vascular disease, n (%) | 20 (33) | 10 (33) | 10 (33) | 0.999 |
| COPD, n (%) | 10 (16) | 6 (20) | 4 (13) | 0.731 |
| Preoperative spirometry | ||||
| FVC (% predicted) | 104 [93–117] | 99 [79–117] | 107 [96–118] | 0.204 |
| FEV1 (%) | 96 [79–109] | 90 [70–105] | 105 [86–116] | 0.061 |
| FEV1/FVC | 75 ± 12 | 77 ± 16 | 74 ± 9 | 0.75 |
| KCO (% predicted) | 74 [62–93] | 69 [58–80] | 86 [67–98] | 0.086 |
| ERV (% predicted) |
BMI body mass index, MRC Medical Research Council Scale, MV mechanical ventilation, OLV one lung ventilation, VC vital capacity, FEV1 forced expiratory volume in the 1st second, FVC forced vital capacity, MEF maximal expiratory flow, ERV expiratory reserve volume
p values are referred to comparison between PEEPINCREMENTAL and PEEPDECREMENTAL group