Figure 8. MH-30 administration reduces cisplatin-induce nephrotoxicity. On day 17 after initial injection of cisplatin, serum was prepared through clotting of whole blood collected from the retro-orbital veins and the kidneys were removed and fixed in 10% buffered formalin for 2 days. (A) The levels of serum BUN and creatinine were analyzed using the AU680 Chemistry System. (B) The paraffin-embedded sections (5 mm thick) were stained with hematoxylin and eosin (H&E) for histopathological examination and observed under light microscope at ´200 magnifications. The result shown is representative cortex from each group. There were twelve mice in each group. Data are presented as the Mean±SD. †p<0.05 and ‡p<0.01 compared with the control group; *p<0.01 compared with the only cisplatin treated group.