Table 2. The univariate and multivariate Cox proportional hazard regression analyses between the clinical related factors and survival in GC patients.
| Variables | Univariate analysis | Multivariate analysis | |
|---|---|---|---|
| Wald χ2 | HR (95%CI) | P | |
| Age (year) | 0.185 | 0.667 | |
| <60 | Reference | ||
| ≥60 | 1.119 [0.672–1.862] | 0.667 | |
| Sex | 0.206 | 0.650 | |
| Male | Reference | ||
| Female | 0.881 [0.51–1.522] | 0.650 | |
| Tumor size (cm) | 4.82 | 0.090 | |
| ≤3 | Reference | ||
| 3–6 | 1.805 [0.954–3.414] | 0.069 | |
| ≥6 | 1.088 [0.493–2.402] | 0.834 | |
| TNM stage (AJCC) | 0.514 | 0.773 | |
| I | Reference | ||
| II | 0.887 [0.474–1.662] | 0.709 | |
| III | 1.136 [0.608–2.121] | 0.689 | |
| Grade (AJCC) | 0.436 | 0.509 | |
| I + II | Reference | ||
| III | 1.188 [0.712–1.984] | 0.509 | |
| Histology | 2.599 | 0.107 | |
| Adenocarcinoma | Reference | ||
| Others | 1.869 [0.874–3.997] | 0.107 | |
| CMTM6 | 10.157 | 0.001 | |
| Low | Reference | ||
| High | 2.221 [1.36–3.628] | 0.001 | |
| PDL1 | 1.256 | 0.262 | |
| Negative | Reference | ||
| Positive | 1.409 [0.774–2.566] | 0.262 | |