Table 3.
The baseline characteristics of all patients who could be assessed for the association between D-dimer trend and all-cause mortality via group-based trajectory modeling. Abbreviations: IQR – interquartile range; VTE – venous thromboembolism.
| Total (n = 368) | Stable D-dimer (n = 275) | Increasing D-dimer (n = 93) | p-Value | |
|---|---|---|---|---|
| Age at diagnosis, median (IQR) | 65 (53–74) | 65 (52–74) | 66 (58–73) | 0.2861 |
| Female, n (%) | 128 (0.0%) | 95 (34.5%) | 33 (35.5%) | 0.8695 |
| Race, n (%) | 0.0014 | |||
| Non-Hispanic White | 111 (30.2%) | 89 (32.4%) | 22 (23.7%) | |
| Black | 79 (21.5%) | 46 (16.7%) | 33 (35.5%) | |
| Other | 162 (44.0%) | 129 (46.9%) | 33 (35.5%) | |
| Unknown | 16 (4.3%) | 11 (4.0%) | 5 (5.4%) | |
| Charlson comorbidity index, median (IQR) | 3 (1–4) | 3 (1–5) | 3 (2–4) | 0.9012 |
| Current smoker | 13 (3.5%) | 11 (4.0%) | 2 (2.2%) | 0.3915 |
| Obese | 144 (39.1%) | 100 (36.4%) | 44 (47.3%) | 0.1566 |
| Prior VTE | 13 (3.5%) | 11 (4.0%) | 2 (2.2%) | 0.4036 |
| On anticoagulant prior to diagnosis | 29 (7.9%) | 27 (9.8%) | 2 (2.2%) | 0.0177 |
| First D-dimer value within 1 week of diagnosis, median (IQR) | 1.4 (0.8–3.1) | 1.1 (0.7–2.1) | 3.0 (1.4–8.0) | <0.0001 |