Table 1.
Baseline and Admission Laboratory Tests
| Test | Reference Range | Baseline (Early April, 2020) | Diagnosis of COVID-19 (Late April, 2020) | Admission (Mid-May, 2020) |
|---|---|---|---|---|
| Days prior to admission | −37 d | −24 d | 0 | |
| WBC (× 103 cells/mm3) | 3.7-10.5 | 11.9 | 7.6 | 10.3 |
| % Neutrophil | 74 | |||
| % Lymphocyte | 20 | |||
| Hemoglobin, g/dL | 11.9-15.5 | 14.5 | 14.0 | 12.5 |
| Platelet, × 103 cells/mm3 | 150-400 | 243 | 196 | 301 |
| CRP (mg/dL) | < 0.5 | < 0.5 | ||
| PT-INR | 1.0 | |||
| Fibrinogen, mg/dL | 194-448 | 262 | ||
| Sodium, mEq/L | 135-145 | 145 | 135 | 138 |
| Potassium, mEq/L | 3.5-5.0 | 3.7 | 3.5 | 4.1 |
| Chloride, mEq/L | 95-107 | 110 | 98 | 107 |
| CO2, mEq/L | 22-29 | 21 | 19 | 16 |
| Urea nitrogen, mg/dL | 10-20 | 23 | 12 | 38 |
| Creatinine, mg/dL | 0.5-1.0 | 1.6 | 1.6 | 3.4 |
| eGFR, mL/min/1.73 m2 | 43 | 43 | 17 | |
| Calcium, mg/dL | 8.5-10.5 | 9.8 | 9.5 | 8.5 |
| Total protein, g/dL | 6.0-8.0 | 7.2 | 5.9 | |
| Albumin, g/dL | 3.4-4.8 | 3.8 | 2.5 (at admission) 2.4 (4 d later) |
|
| Cholesterol, mg/dL | 261 | |||
| LDH, IU/L | 135-214 | 278 | ||
| Ferritin, ng/mL | 13-150 | 564 | ||
| C3, mg/dL | 90-180 | 81 | ||
| C4, mg/dL | 16-47 | 24 | ||
| ANA | < 1:80 | < 1:80 | ||
| DS-DNA, IU/mL | 1-4 | 1 | ||
| Cryoglobulin | negative | negative | ||
| SPEP | negative | negative | ||
| UPEP | negative | negative | ||
| Serum-free K/L LC ratio | 0.26-1.65 | 2.39 | ||
| Hepatitis B virus infection | negative | negative | ||
| Hepatitis C virus infection | negative | negative | ||
| HIV infection | negative | negative | ||
| BKV PCR | negative | negative | ||
| Tacrolimus, 12-h trough, ng/mL | 5.8 | 6.0 | ||
| Urinalysis with microscopy | ||||
| Occult blood | negative | trace | ||
| Protein | negative | 4+ | ||
| White blood cell, /HPF | < 5 | 0-2 | ||
| Red blood cell, /HPF | < 5 | 0-2 | ||
| Urine creatinine, mg/dL | 146 | 55 | ||
| Spot urine protein, mg/dL | 25 | 437 | ||
| UPCR, g/g creatinine | 0.2 | 8.0 | ||
| 24-h urine protein, g/24h | 6.3 |
Abbreviations: ANA, antinuclear antibody; BKV, BK polyomavirus; COVID-19, coronavirus disease 2019; CRP, C-reactive protein; DS-DNA, double-stranded DNA antibody; eGFR, estimated glomerular filtration rate; HPF, high-power field; K/L LC, serum free kappa lambda light chain; LDH, lactate dehydrogenase; PCR, polymerase chain reaction; PT-INR, prothrombin time international normalization ratio; SPEP, serum protein electrophoresis; UPCR, urine protein creatinine; UPEP, urine protein electrophoresis; WBC, white blood cell count.