Table 2.

Single Marker Allelic Association of Response to Anti-VEGF Treatment of Patients With AMD

Marker	Chr	Gene	Relative Position	Risk Allele	Wild-Type Allele	Freq Pos	Freq Neg	P	Odds Ratio
rs1061170	1	CFH	Y402H	C	T	0.55	0.50	0.45	1.20
rs10490924	10	ARMS2	A69S	T	G	0.42	0.41	0.81	1.06
rs3750848	10	ARMS2	Intron	G	T	0.43	0.39	0.48	1.19
del443ins54	10	ARMS2 3′	untranslated region	2	1	0.42	0.40	0.70	1.10
rs3793917	10	—	Intergenic	G	C	0.41	0.41	0.95	1.02
rs11200638	10	HTRA1	Promoter	A	G	0.41	0.41	0.97	0.99
rs932275	10	HTRA1	Intron	A	G	0.41	0.39	0.79	1.07

1, no indel for AMD; 2, indel for AMD; freq pos, frequency of the risk alleles in cases; freq neg, frequency of the risk alleles in controls.