Table 3.
Marker | Risk Allele | Wild-Type Allele | Genotype for Positive Responders | Genotype for Negative Responders | Allelic P | Total Inj P | ΔVA P |
---|---|---|---|---|---|---|---|
rs1061170 | C | T | 27/42/19 | 15/25/15 | 0.47 | 0.95 | 0.25 |
rs10490924 | T | G | 21/37/35 | 10/26/20 | 0.82 | 0.38 | 0.43 |
rs3750848 | G | T | 20/36/32 | 9/24/21 | 0.50 | 0.82 | 0.64 |
del443ins54 | 2 | 1 | 22/35/36 | 10/25/21 | 0.72 | 0.26 | 0.41 |
rs3793917 | G | C | 19/38/35 | 10/25/20 | 0.95 | 0.33 | 0.32 |
rs11200638 | A | G | 19/38/36 | 11/24/21 | 0.97 | 0.38 | 0.29 |
rs932275 | A | G | 20/36/37 | 10/24/22 | 0.80 | 0.49 | 0.48 |
P value of significance by genotypic association on response by χ2 test, genotypic association on total number of injections, and on change in visual acuity by logistic regression are indicated.
1, no indel for AMD; 2, indel for AMD.