Table 3.
Colistin-sensitive group (n=57) |
Colistin-resistant group (n=20) |
P |
|
---|---|---|---|
Antibiotics last 3 months |
4 (7) |
3 (15) |
.367 |
Antibiotics during hospitalization prior to infection |
57 (100) |
20 (100) |
– |
Use of carbapenems |
17 (30) |
12 (60) |
.003 |
Duration of carbapenem use (days) |
0 (0, 2) |
4 (0, 8) |
.012 |
Use of antipseudomonal penicillins |
17 (30) |
12 (60) |
.030 |
Duration of antipseudomonal penicillin use (days) |
0 (0, 2) |
3 (0, 7) |
.023 |
Use of quinolones |
12 (21) |
11 (55) |
.009 |
Duration of quinolone use (days) |
0 (0, 0) |
3 (0, 12) |
.002 |
Use of cephalosporin 3d generation |
24 (42) |
5 (25) |
.194 |
Duration of cephalosporin 3d generation use (days) |
0 (0, 4) |
0 (0, 1) |
.114 |
Use of cephalosporin fourth generation |
4 (7) |
7 (35) |
.005 |
Duration of cephalosporin fourth generation use (days) |
0 (0, 0) |
0 (0, 4) |
.003 |
Use of colistin |
12 (21) |
8 (40) |
.138 |
Duration of colistin use (days) |
0 (0) |
0 (0, 4) |
.087 |
Use of tygecycline |
0 (0) |
8 (40) |
<.001 |
Duration of tygecycline use (days) |
0 (0, 0) |
0 (0, 7) |
<.001 |
Use of aminoglycosides |
1 (2) |
4 (20) |
.015 |
Duration of aminoglycoside use (days) |
0 (0, 0) |
0 (0, 0) |
.005 |
Data are presented as median (25 %, 75 % quartiles) or n (%); P, comparison between the two groups. Appropriate antibiotic therapy referred to the administration at least one of the in vitro active antimicrobials against the study isolates for at least 48 h. Results by univariate analysis.