Table 3:
Traits | rg ± SE | GCP ± SE |
---|---|---|
Intracranial volume | ||
IQ | 0.291 ± 0.107 | 0.746 ± 0.146 |
EduYears | 0.411 ± 0.077 | 0.721 ± 0.174 |
ICV + HC | ||
IQ | 0.306 ± 0.083 | 0.495 ± 0.137 |
EduYears | 0.353 ± 0.064 | 0.450 ± 0.136 |
rg, the genetic correlation estimated by bivariate LD Score regression between the measures of head size (Taal et al., 2012; Hibar et al., 2015) and cognition (Lee et al., 2018); GCP, the genetic causality proportion, which ranges between zero (genetic variation acts purely as a confounder X ← G → Y ) and one (joint genetic influences act purely through the causal chain G → X → Y ); ICV + HC, GWAS meta-analysis of adult intracranial volume and infant head circumference.