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Role of EAEC adhesins in adherence to human colonoids. Adherence to colonoid monolayers seeded in collagen-coated wells in a 96-well plate after 3 h of incubation. Lines 70C (blue) and 75C (green) were derived from two different donors. One-way ANOVA was performed on log-transformed data followed by Bonferroni’s test for multiple comparisons: *, P ≤ 0.05; **, P ≤ 0.01; ***, P ≤ 0.001; ****, P ≤ 0.0001, compared to nonmotile WT infection of each colonoid line.
