Table 3.

Secondary outcomes (quality of life and exploratory findings) at weeks 8, 26 and 52

Visit	Oral route		IM route		P value	Mean difference (95% CI)
	N	Mean (SD)	N	Mean (SD)
Quality of life (EQ-5D-5L Index)
Baseline	139	0.855 (0.139)	137	0.817 (0.197)	0.066	0.038 (−0.002 to 0.078)
Week 8	134	0.853 (0.158)	130	0.822 (0.204)	0.173	0.031 (−0.013 to 0.075)
Week 26	128	0.853 (0.153)	122	0.826 (0.191)	0.219	0.027 (−0.016 to 0.070)
Week 52	112	0.824 (0.179)	117	0.823 (0.194)	0.958	0.001 (−0.047 to 0.049)

GLM, generalised linear model; IM, intramuscular.