| At least one altered sign (glossitis and/or altered vibration sensitivity and/or altered position sensitivity) | ||||||
| Visit | N | n (%) | N | n (%) | P value | Proportion difference (95% CI) |
| Baseline | 140 | 16 (11.4) | 143 | 21 (14.7) | 0.416 | −3.3 (−11.1 to 4.6) |
| Week 8 | 135 | 15 (11.1) | 130 | 13 (10.0) | 0.769 | 1.1 (−6.3 to 8.5) |
| Week 26 | 131 | 14 (10.7) | 122 | 12 (9.8) | 0.824 | 0.9 (−6.6 to 8.3) |
| Week 52 | 122 | 14 (12.5) | 117 | 9 (7.7) | 0.226 | 3.8 (−3.7 to 11.2) |
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