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. 2020 Aug 12;12:7219–7230. doi: 10.2147/CMAR.S251348

Figure 2.

Figure 2

RNA-seq to explore the regulation network associated with ENO1.

Notes: Heat map showing differentially expressed noncoding RNAs (A) and mRNAs (B), when comparing OSCC with OLP. Red denotes high expression and blue denotes low expression. The transcriptome sequencing reveals 6734 differentially expressed mRNA genes (C), 3327 upregulateregulated and 3408 downregulateregulated; and 1985 differentially expressed ncRNAs (D), 608 upregulateregulated and 1377 downregulateregulated. (E) There is a highly positive correlation between the expression of circ-AMOTL1 and ENO1 in TCGA head and neck squamous cell carcinoma database. (F) Binding sites of ENO1 and miR-22-3p. (G) Binding sites of ENO1 and miR-1294. (H) Binding sites of circ-AMOTL1 and miR-22-3p. (I) Binding sites of circ-AMOTL1 and miR-1294.

Abbreviations: OLP, oral lichen planus; OSCC, oral squamous cell carcinoma.